Neuroactive steroids are also called as neurosteroids . They are endogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors. Neuroactive steroid refers to steroids that are synthesized by an endocrine gland that reach the brain through the bloodstream and have effects on brain function. Neurosteroids have a wide range of potential clinical applications from sedation to treatment of epilepsy and traumatic brain injury. Ganaxolone is a synthetic analog of the endogenous neurosteroid. Allopregnanolone is under investigation for the treatment of epilepsy.
Five athletes tested positive for the stimulant bromantan and were disqualified by the IOC, but later reinstated after an appeal to the Court of Arbitration for Sport: swimmers Andrey Korneyev and Nina Zhivanevskaya , Greco-Roman wrestler Zafar Guliyev and sprinter Marina Trandenkova , all from Russia, and the Lithuanian track cyclist Rita Razmaitė . Dr. Vitaly Slionssarenko, physician to the Lithuanian cycling team and team coach Boris Vasilyev were expelled from the games.    The CAS overturned the IOC decision, because bromantan had only recently been added to the prohibited list,  and the athletes and officials were reprimanded.    The Russians had argued that bromantans wasn't a stimulant and thus not banned.