A lot of it really depends on the amount of caffeine in the drink. If you read my comments below, you’ll see how much caffeine it takes to increase your cortisol by 30%. You have to remember that supplement companies, in general, don’t care about your health or even your performance. What they care about is that you “feel” something when using their product and therefore you “believe” it’s doing some good so that you come back and buy their product again and again. That’s not to say that caffeine doesn’t have performance benefits because the literature is very clear that it does, but it’s a double-edged sword. So you have to weigh the pros and the cons with it and decide for yourself if it’s worth it based on your own individual performance and body transformation goals.
Hypercalcemia may develop both spontaneously and as a result of androgen therapy in women with disseminated breast carcinoma. If it develops while on this agent, the drug should be discontinued. Caution is required in administering these agents to patients with cardiac, renal or hepatic disease. Cholestatic jaundice is associated with therapeutic use of anabolic and androgenic steroids. Edema may occur occasionally with or without congestive heart failure. Concomitant administration of adrenal steroids or ACTH may add to the edema. In children, anabolic steroid treatment may accelerate bone maturation without producing compensatory gain in linear growth. This adverse effect may result in compromised adult stature. The younger the child the greater the risk of compromising final mature height. The effect on bone maturation should be monitored by assessing bone age of the wrist and hand every six months. This drug has not been shown to be safe and effective for the enhancement of athletic performance. Because of the potential risk of serious adverse health effects, this drug should not be used for such purpose.
The androgenic:anabolic ratio of an AAS is an important factor when determining the clinical application of these compounds. Initial steroid research sought to synthesize a compound which retained a high degree of anabolic activity coupled with a diminished androgenic activity, the goal being to produce a compound with a high anabolic yet low androgenic effect, or a high A/A ratio. Since steroids were intended for medical treatment patients could include men and women, and even children. It was therefore important to avoid any androgenic effects when providing anabolic treatment. ( Edited by WUMEITECH . )